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Year Number of Results
2001 1
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2010 2
2011 1
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2018 1
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11 results

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Page 1
Bioinformatic analysis of gene expression profiling of intracranial aneurysm.
Bo L, Wei B, Wang Z, Li C, Gao Z, Miao Z. Bo L, et al. Mol Med Rep. 2018 Mar;17(3):3473-3480. doi: 10.3892/mmr.2017.8367. Epub 2017 Dec 29. Mol Med Rep. 2018. PMID: 29328431 Free PMC article.
On analysis of the transcription factor regulatory network, 6 transcription factors (HNF6, HNF4A, E2F4, YY1, H4 and H31T) and a regulatory pathway (HNF6-HNF4-E2F4) were identified. The results of the present study suggest that activating transcription factor-5, Jun …
On analysis of the transcription factor regulatory network, 6 transcription factors (HNF6, HNF4A, E2F4, YY1, H4 and H31T) and a regul …
Unraveling the genetics of otitis media: from mouse to human and back again.
Rye MS, Bhutta MF, Cheeseman MT, Burgner D, Blackwell JM, Brown SD, Jamieson SE. Rye MS, et al. Mamm Genome. 2011 Feb;22(1-2):66-82. doi: 10.1007/s00335-010-9295-1. Epub 2010 Nov 25. Mamm Genome. 2011. PMID: 21107580 Review.
Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity. Acute OM and chronic OM with effusion (COME) affect the majority of children by school age and have heritability estimates of 40 …
Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle …
CD133 expression is associated with less DNA repair, better response to chemotherapy and survival in ER-positive/HER2-negative breast cancer.
Sato T, Oshi M, Huang JL, Chida K, Roy AM, Endo I, Takabe K. Sato T, et al. Res Sq [Preprint]. 2024 Mar 27:rs.3.rs-4148608. doi: 10.21203/rs.3.rs-4148608/v1. Res Sq. 2024. PMID: 38585981 Free PMC article. Preprint.
CD133-low BC was also linked with enrichment of genes related to DNA repair, such as BRCA1, E2F1, E2F4, CDK1/2. On the other hand, CD133-high tumors had proinflammatory microenvironment, higher activity of immune cells, and higher expression of genes related to inflamma …
CD133-low BC was also linked with enrichment of genes related to DNA repair, such as BRCA1, E2F1, E2F4, CDK1/2. On the other hand, CD …
Motor neurons from ALS patients with mutations in C9ORF72 and SOD1 exhibit distinct transcriptional landscapes.
Wong CO, Venkatachalam K. Wong CO, et al. Hum Mol Genet. 2019 Aug 15;28(16):2799-2810. doi: 10.1093/hmg/ddz104. Hum Mol Genet. 2019. PMID: 31107959 Free PMC article.
Functional annotation of differentially expressed genes in induced pluripotent stem cell (iPSC)-derived motor neurons generated from patients with mutations in C9ORF72 (C9-ALS) suggests elevated expression of genes that pertain to extracellular matrix (ECM) and cell adhesion, …
Functional annotation of differentially expressed genes in induced pluripotent stem cell (iPSC)-derived motor neurons generated from patient …
Nitric oxide-dependent downregulation of BRCA1 expression promotes genetic instability.
Yakovlev VA. Yakovlev VA. Cancer Res. 2013 Jan 15;73(2):706-15. doi: 10.1158/0008-5472.CAN-12-3270. Epub 2012 Oct 29. Cancer Res. 2013. PMID: 23108140 Free PMC article.
Elevated levels of nitric oxide (NO) and reactive nitrogen species (RNS) may link inflammation to the initiation, promotion, and progression of cancer. ...RBL2/E2F4 formation in turn led to a shift in BRCA1 promoter occupancy from complexes containing activator E2F1 …
Elevated levels of nitric oxide (NO) and reactive nitrogen species (RNS) may link inflammation to the initiation, promotion, and prog …
A multidimensional integration analysis reveals potential bridging targets in the process of colorectal cancer liver metastasis.
Gao B, Yu T, Xue D, Sun B, Shao Q, Choudhry H, Marcus V, Ragoussis J, Zhang Y, Zhang W, Gao ZH. Gao B, et al. PLoS One. 2017 Jun 19;12(6):e0178760. doi: 10.1371/journal.pone.0178760. eCollection 2017. PLoS One. 2017. PMID: 28628609 Free PMC article.
Primary tumor samples and liver metastasis samples had modules with significant overlap and crosstalk from which we identified several bridging genes (e.g. KNG1 and COX5B), transcription factors (e.g. E2F4 and CDX2), microRNAs (e.g. miR-590-3p and miR-203) and lncRNAs (e.g …
Primary tumor samples and liver metastasis samples had modules with significant overlap and crosstalk from which we identified several bridg …
Macrophage migration inhibitory factor MIF interferes with the Rb-E2F pathway.
Petrenko O, Moll UM. Petrenko O, et al. Mol Cell. 2005 Jan 21;17(2):225-36. doi: 10.1016/j.molcel.2004.11.052. Mol Cell. 2005. PMID: 15664192 Free article.
The basis for this transformation resistance is a perturbed function of the C-terminal Rb binding region of E2F4. However, inactivation of Rb or substitution of the E2F4 C-terminal domain by the E2F1 C-terminal region rescues the transformation defect. ...A proinfla …
The basis for this transformation resistance is a perturbed function of the C-terminal Rb binding region of E2F4. However, inactivati …
The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells.
Hansen SN, Ehlers NS, Zhu S, Thomsen MB, Nielsen RL, Liu D, Wang G, Hou Y, Zhang X, Xu X, Bolund L, Yang H, Wang J, Moreira J, Ditzel HJ, Brünner N, Schrohl AS, Stenvang J, Gupta R. Hansen SN, et al. BMC Genomics. 2016 Jun 9;17:442. doi: 10.1186/s12864-016-2749-4. BMC Genomics. 2016. PMID: 27277198 Free PMC article.
At higher docetaxel concentration MCF-7 subclones exhibited a copy number loss in E2F4, and the gene encoding this important transcription factor was down-regulated in MCF-7 resistant cells. ...
At higher docetaxel concentration MCF-7 subclones exhibited a copy number loss in E2F4, and the gene encoding this important transcri …
Silica induces cell cycle changes through PI-3K/AP-1 pathway in human embryo lung fibroblast cells.
Jia X, Liu B, Ye M, Liu H, Shi X. Jia X, et al. Cell Biochem Funct. 2010 Oct;28(7):613-9. doi: 10.1002/cbf.1699. Cell Biochem Funct. 2010. PMID: 20941752
Exposure to silica is associated with progressive pulmonary inflammation and fibrosis. Our previous study had demonstrated silica exposure could cause cell cycle alternation and activator protein-1 (AP-1) activation. ...
Exposure to silica is associated with progressive pulmonary inflammation and fibrosis. Our previous study had demonstrated silica exp …
The interferon-inducible p202a protein modulates NF-kappaB activity by inhibiting the binding to DNA of p50/p65 heterodimers and p65 homodimers while enhancing the binding of p50 homodimers.
Ma XY, Wang H, Ding B, Zhong H, Ghosh S, Lengyel P. Ma XY, et al. J Biol Chem. 2003 Jun 20;278(25):23008-19. doi: 10.1074/jbc.M302105200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676938 Free article.
Thus, the binding of p202a results in the inhibition of the sequence-specific binding to DNA of the c-Fos, c-Jun, E2F1, E2F4, MyoD, myogenin, and c-Myc transcription factors. This study concerns the mechanisms by which p202a inhibits the activity of NF-kappaB, a transcript …
Thus, the binding of p202a results in the inhibition of the sequence-specific binding to DNA of the c-Fos, c-Jun, E2F1, E2F4, MyoD, m …
11 results